



ESTETICUS Stimulating levelling serum, 0.3% adapalene acid ester, 5% collagen polypeptide complex, 0.25% PDRN 30ml
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Suitable for mature skin – reduces visible pores, imperfections and signs of ageing while supporting firmness, regeneration and an even, healthy complexion
The Stimulating Balancing Serum is an advanced formula designed for skin requiring renewal, smoothing and tone correction. A synergistic blend of next-generation active ingredients enhances the skin’s structure, elasticity and density, while minimising the risk of irritation. It is a perfect solution for sensitive complexions that struggle to build tolerance to first-generation retinoids yet need intensive rejuvenation and revitalisation.
Key ingredients:
- 0.3% Adapalene Ester (Adapinoid®) - a third-generation retinoid precursor that, through bioactivation, effectively penetrates into the deeper layers of the epidermis. It works on multiple levels – addressing signs of ageing, pigmentation and imperfections. By stimulating collagen synthesis, it improves skin texture and firmness. It promotes cellular renewal and regulates sebum production, reducing the appearance of blackheads and micro-inflammations. It evens out the complexion by diminishing discolouration and redness, providing highly effective care with minimal irritation, making it ideal for sensitive skin.
- 0.25% Pure PDRN - a sodium salt of deoxyribonucleic acid with strong regenerative and anti-ageing properties. It provides an instant tightening effect and supports the skin’s natural repair processes. It also acts as a powerful antioxidant, protecting against oxidative stress and UV-induced damage. With its hygroscopic properties, it binds water in the epidermis, deeply hydrating and soothing micro-inflammatory conditions.
- 5% Bio-compatible Collagen Polypeptide Complex - reinforces the dermo-epidermal junction, ensuring skin elasticity and resilience. It protects collagen fibres from degradation, supports repair mechanisms and boosts collagen biostimulation, helping to visibly smooth fine lines and wrinkles.
- Ceramide Analogue - mimics the function of natural skin ceramides, rebuilding the hydrolipid barrier. It soothes and hydrates dry skin while improving its resistance to external factors.
Results:
- visibly rejuvenated skin with slowed ageing processes,
- improved firmness and elasticity,
- reduction of imperfections and uneven texture,
- refined pores and balanced sebum production,
- smoother, more uniform complexion.
Suitable for skin that is:
- lacking firmness and elasticity,
- showing first signs of ageing,
- wrinkled or mature,
- with imperfections, congestion or uneven texture,
- with enlarged pores and excess sebum production.
How to use:
Apply two pumps of serum in the evening to cleansed skin of the face, neck and décolletage, avoiding the eye and lip area. During adapalene ester treatment, avoid direct sun exposure and always protect the skin with a minimum SPF 50 – for example, the Toning Protective Emulsion SPF 50+. Do not apply to irritated or damaged skin.
How to carry out the adapalene ester (Adapinoid®) treatment:
Begin by applying every third evening for the first two weeks. If no irritation occurs, reduce the interval by one day after every two weeks of use as follows:
- Weeks 1–2 – every third evening,
- Weeks 3–4 – every other evening.
Once tolerance is established and the serum is used four times a week, you may move on to a higher concentration (0.5%) available in the COSMETOLOGY version, following its dedicated usage schedule.
Warnings and recommendations:
- Due to the presence of adapalene ester, the product should not be used during pregnancy.
- During breastfeeding, consult your doctor before use.
- Daily use of high-protection sunscreen (minimum SPF 50), e.g. Light Protective Emulsion SPF 50+ PPD 52.3, is essential.
- The serum can be used year-round; however, if adequate UV protection is not possible, start the treatment in autumn or winter.
- Temporary redness, dryness or flaking may occur in the first weeks – this is a natural process of building skin tolerance.
- Complementary use of moisturising and barrier-repair products is recommended.
- Dermatologically tested on sensitive skin.
- Fragrance-free formula designed to minimise the risk of allergic reactions.
FAQ
Can it be used during pregnancy or breastfeeding?
Products containing retinoids should not be used during pregnancy. During breastfeeding, use is not contraindicated, but it is advisable to consult a healthcare professional before introducing the product.
Does the skin need to build tolerance to Adapinoid?
Yes. As with any retinoid, the skin must gradually build tolerance to Adapinoid®. Begin by applying every two to three evenings and reduce the interval as tolerance improves.
What should not be combined with this serum?
It is not recommended to use in the same routine with products containing Vitamin C (ascorbic acid), azelaic acid or AHA/BHA/PHA acids.
How long should I wait before applying other skincare products?
Wait until the serum is fully absorbed before layering additional products.
Can the serum be used during the day?
No – this serum is intended exclusively for evening use.
Expiry date: min. 3 months unless stated differently in the title or description
Aqua, Crambe Abyssinica Seed Oil, Pentylene Glycol, Polyglyceryl-6 Stearate, C13-16 Isoalkane, Meadowfoam Estolide, Propylheptyl Caprylate, Silybum Marianum Ethyl Ester, Jojoba Oil/Macadamia Seed Oil Esters, Glycerin, Sh-Polypeptide-69, Squalene, Oleyl Adapalenate, Phytosterols, Sodium DNA, Phytosteryl Macadamiate, Cetearyl Alcohol, Tocopherol, Citric Acid, Heptyl Undecylenate, Polyglyceryl-6 Behenate, Xanthan Gum, Sodium Benzoate, Hydroxyacetophenone.
The product label is the authoritative source of ingredient information. Our website descriptions are based on manufacturer data; despite our best efforts, minor formulation changes by the manufacturer may not be immediately reflected online.