


ESTETICUS Stimulating levelling serum, 0.5% adapalene acid ester, 10% collagen polypeptide complex, 0.5% PDRN, retinal 30ml
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Stimulating Smoothing Serum – suitable for mature and acne-prone skin, reduces pore visibility, imperfections and signs of ageing, supports firmness, regeneration and an even, healthy complexion!
The stimulating smoothing serum is an advanced formula designed for skin in need of smoothing, regeneration and evening out tone. With two forms of retinoids (I and III generation), it provides strong anti-ageing effects, reducing fine lines and wrinkles. The synergistic combination of next-generation active ingredients improves skin elasticity and firmness, while evening out skin tone, all with minimal irritation risk.
Key Ingredients:
- 0.5% Adapalene Ester (Adapinoid®) - a precursor of third-generation retinoid, bioactivated to penetrate deep into the skin. It acts on multiple levels: reducing signs of ageing, pigmentation and blemishes. It boosts collagen synthesis, enhances skin structure, regulates sebum production, and supports exfoliation. It evens skin tone by reducing discoloration and redness, making it ideal for sensitive skin with minimal irritation.
- 0.5% pure PDRN - sodium salt of deoxyribonucleic acid with regenerative and anti-ageing properties. Instantly tightens skin, stimulates repair processes, acts as a powerful antioxidant protecting against oxidative stress and UV damage, and binds water in the epidermis, providing hydration and soothing microinflammation.
- 10% collagen polypeptide complex - supports dermo-epidermal junction, providing firmness and elasticity, protecting collagen fibres from degradation, and enhancing collagen biostimulation, contributing to visible smoothing of fine lines and wrinkles.
- 0.05% retinal - a first-generation retinoid with anti-wrinkle and firming effects. It regulates sebum production, helping to reduce blemishes and minimise pore visibility. Synergistic action with adapalene ester accelerates epidermal renewal, visibly improving skin structure.
- Postbiotic exosomes - microscopic particles ensuring deep skin penetration. They enhance elasticity, reduce wrinkle appearance, brighten skin tone and strengthen the skin barrier.
Results:
- Visibly rejuvenated skin and slowed ageing processes,
- Reduced blemishes,
- Even skin texture,
- Minimised pores and balanced sebum production,
- Noticeably firmer and more elastic skin,
- Tightened and smoother skin,
- Reduced fine lines and wrinkles,
- Lower tendency for new wrinkle formation,
- Stimulated skin repair processes.
Suitable for skin:
- with blemishes, blackheads or uneven texture,
- with enlarged pores,
- lacking firmness or elasticity,
- showing early signs of ageing,
- with wrinkles or mature,
- loose or rough.
How to use:
Apply an appropriate amount of serum (approx. 2 pumps) in the evening to cleansed face, neck and décolleté, avoiding eye and lip areas. During adapalene ester and retinal treatment, avoid direct sun exposure and apply SPF 50+ protection, e.g., Tinted SPF 50+ Protective Emulsion. Do not apply to damaged or irritated skin.
How to conduct treatment with Adapalene Ester (Adapinoid®) and Retinal combination?
For the first two weeks, apply the serum every fourth evening. If no adverse reactions occur, reduce the interval between applications by one day every two weeks:
- Week 1–2: every 4th evening,
- Week 3–4: every 3rd evening,
- Week 5–6: every 2nd evening.
Warnings and recommendations:
- Not recommended during pregnancy. Consult a doctor if breastfeeding.
- Daily SPF 50+ protection is required, e.g., Light Protective Emulsion SPF 50+ PPD 52.3.
- Treatment can be continued year-round; start in autumn–winter if sun protection is insufficient in summer.
- Initial redness, dryness, flaking or irritation may occur – natural adaptation to retinoids. Complement with moisturisers and barrier-repair products.
- Dermatologically tested on sensitive skin.
- Fragrance-free; formulation minimises allergy risk.
FAQ
Can it be used during pregnancy or breastfeeding?
Retinoid products should not be used during pregnancy. Breastfeeding is not an absolute contraindication, but consultation with a healthcare professional is recommended.
Is tolerance required for Adapinoid®?
Yes. As with all retinoids, tolerance should be built gradually. The Cosmetology variant should be applied every 4th–5th evening, reducing the interval by one day every two weeks.
Which products should not be combined with this serum?
Do not combine in the same skincare routine with vitamin C (ascorbic acid), azelaic acid, AHA/BHA/PHA acids, or copper peptides.
Why is retinal included in the formula?
0.05% retinal enhances anti-ageing and anti-acne effects and activates all retinoic acid receptors (RARs).
Can the serum be used during the day?
No – the serum contains Adapinoid®, a third-generation retinoid, which, like all retinoids, is intended for evening use only.
Expiry date: min. 3 months unless stated differently in the title or description
Aqua, Crambe Abyssinica Seed Oil, Pentylene Glycol, Polyglyceryl-6 Stearate, Glycerin, C13-16 Isoalkane, Propylheptyl Caprylate, Meadowfoam Estolide, Silybum Marianum Ethyl Ester, Lactobacillus Extracellular Vesicles, Jojoba Oil/Macadamia Seed Oil Esters, Sh-Polypeptide-69, Squalene, Oleyl Adapalenate, Phytosterols, Sodium DNA, Phytosteryl Macadamiate, Cetearyl Alcohol, Tocopherol, Retinal, Phospholipids, Ascorbic Acid, Heptyl Undecylenate, Polyglyceryl-6 Behenate, Caprylic/Capric Triglyceride, Xanthan Gum, Citric Acid, Sodium Benzoate, Butylene Glycol, 1,2-Hexanediol, Hydroxyacetophenone.
The product label is the authoritative source of ingredient information. Our website descriptions are based on manufacturer data; despite our best efforts, minor formulation changes by the manufacturer may not be immediately reflected online.